List of Treatments for Seizures

This page offers a list of FDA- approved treatments often used in those with LGS. Not all medications used in LGS are listed here. This list reflects U.S. FDA-approved medications. For info on epilepsy treatments in the U.K. visit this page.

For a general overview of LGS treatment, visit our How LGS is Treated page here.

Medications for Seizures in LGS

  • Epidiolex
  • Epitol
  • Tegretol
  • Carbatrol
  • Onfi (pill)
  • Sympazan (dissolvable strip)
  • Felbatol
  • Fintepla
  • Lamictal
  • Banzel
  • Topamax (pill)
  • Eprontia (liquid)

Medications for Seizures (not specifically for Seizures in LGS but for seizures in General)

  • Briviact
  • Xcopri
  • Klonopin
  • Depacon
  • Depakote
  • Depakote ER
  • Aptiom
  • Zarontin
  • Neurontin
  • Vimpat
  • Keppra
  • Keppra XR
  • Ativan
  • Oxtellar XR
  • Trileptal
  • Fycompa
  • Phenobarbital
  • Dilantin
  • Lyrica
  • Mysoline
  • Diacomit
  • Gabitril
  • Qudexy XR
  • Trokendi XR
  • Depakene
  • Sabril
  • Zonegran (pill)
  • Zonisade (liquid)

Medications for Seizure Clusters

Dietary Treatments for Seizures

Dietary therapy is an approach to help control seizures, usually in conjunction with seizure medications.

Neuromodulation Treatments for Seizures

Surgical Options for Seizures

Clinical Trials in LGS

Research is ongoing to find novel, innovative treatments for LGS. Clinical trials are research studies performed in those with LGS. They scientifically evaluate a medical or surgical intervention. They are the primary way that researchers find out if a new treatment, like a new drug, diet, or medical device is safe and is effective in reducing seizures in those with LGS.


This page lists FDA-approved anti-seizure medications in the U.S.

For information about treatment in the UK, visit this page.

The information here is not intended to provide diagnosis, treatment, or medical advice and should not be considered a substitute for advice from a healthcare professional. The content provided is for informational purposes only. LGS Foundation is not responsible for actions taken based on the information included on this webpage. Please consult with a physician or other healthcare professional regarding any medical or health related diagnosis or treatment options.

Updated 8/27/22