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© 2019 LGS FOUNDATION

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LGS Foundation Research Grant Program

Our 2019 Research Grant Cycle is Now CLOSED

The LGS Foundation's seed grant program awards one-year research grants up to $30,000 and two-year grants up to $50,0000 (the LGS Foundation does not permit indirect costs) to young investigators, physician residents, and clinicians who are interested in studying Lennox-Gastaut Syndrome. Our seed grants are intended to help researchers explore novel ideas and answer questions related to the clinical aspects, therapies and/or genetic causes of LGS.


Grant recipients are asked to give a presentation at the LGS Foundation's research meeting at the American Epilepsy Society the following year to discuss their work.

The LGS Foundation does not require an LOI. However, we will evaluate LOI's from investigators prior to submission of a full application.

Areas of Interest:

  • Causes of LGS and increasing our understanding of the underlying biology

  • Evolution of LGS from intractable seizures to Slow Spike & Wave on EEG

  • Evolution of tonic seizure (GPFA on EEG) in LGS

  • Evolution of multiple seizure types in young children, which may lead to future LGS

  • Understanding convulsive/non-convulsive status epilepticus and cluster seizures in LGS

  • Therapies to prevent or treat Lennox-Gastaut Syndrome

  • Quality of Life for individuals living with LGS and their families

  • Epidemiology and better data collection/management of data from individuals of LGS

2019 FUNDING PROGRAM

Program Opens - February 1, 2019

Full Applications Due - June 1, 2019

Award Announcement - July 15, 2019

Anticipated Project Start Date - September 15, 2019

Click here for full RFA 

2018 Recipient

Kay-Marie Lamar, PhD

Northwestern University

"Defining the Molecular Mechanisms of CHD2 in LGS"

2017 Recipients

Vanesa Nieto-Estevez, PhD

UT Southwestern Medical Center

"Modeling Lennox-Gastaut Syndrome in Human Cerebral Organoids"

Aaron Warren, PhD Candidate

Melbourne Brain Centre

"Identifying neuroimaging predictors of treatment outcomes following deep brain stimulation in patients with Lennox-Gastaut syndrome"

2016 Recipients

Nicholas Poolos, MD, PhD

University of Washington

Department of Neurology

"Large scale analysis of antiepileptic drug efficacy in Lennox-Gastaut Syndrome" 

2015 Recipients

Robert Hunt, PhD

University of California Irvine

Department of Anatomy & Neurobiology

Robert Hunt Lab 

"CHD2 model for LGS" 

 

Candace Myers, PhD

University of Washington 

Department of Pediatrics, Division of Genetic Medicine

"Identifying Genetic Causes of LGS" 

 

2014 Recipients

Grone, Brian, PhD

Epilepsy Research Laboratory

Department of Neurological Surgery

University of California, San Francisco

*A Zebrafish Model for LGS*

 

Thiele, Elizabeth, MD, PhD

Director, Pediatric Epilepsy Program

Massachusetts General Hospital 

"Low Glycemic Index Treatment in Patients with LGS"

 

 

Seed Grants

 

Available to young and established investigators. No indiret costs are awarded. LOI's are not required but the LGSF will review an LOI prior to submission of full proposal.

Up to $30,000 - One Year Grant

Post-Doctoral Fellowships

 

PhDs or MDs are encouraged to apply. The grant recipient must spend at least 40% of their professional time engaged in activities related to Lennox-Gastaut Syndrome throughout the duration of their award. Applications must show relevance to one of the LGSF's targeted research areas.

$25,000/year - Two Year Grant

2019 Cycle Opens February 1, 2019.  Application Deadline June 1, 2019.   Awards Announced July 15, 2019

APPLICATION GUIDELINES

LOI Information

 

NOTE: LOIs are welcome but not required.

 

LOI must clearly outline hypothesis and aims and include description of how research will benefit patients with LGS. Maximum 2 pages.

 

 

LOI deadline: April 1, 2019

 

 

Application Instructions:

  • Applications must be submitted by the deadline to Tracy@LGSfoundation.org and must include the following.

  • Title Page: Enter proposal title and PI information.

  • Abstract: Provide a lay summary and a scientific summary of the project.

  • Budget Period Detail: Provide a detailed budget and justification. All expenses must in U.S. dollars.

  • Proposal (NIH format is acceptable)

  • Biosketch for each PI

  • Letters of support or collaboration as relevant

Application Deadline is June 1, 2019.

Click here for full RFA 

International Applicants Welcome. Please submit complete packet of documents to:

tracy@lgsfoundation.org