Treatments for LGS

Ganaxolone (Ztalmy)

New Treatment for Seizures in CDKL5 Deficiency Disorder (a genetic cause of seizures that can lead to LGS)

What is Ganaxolone? LGS is tough. Finding information shouldn’t be. That is why we provide information about this and other medications often used in LGS. We hope you find this information useful as you navigate your LGS journey. Ganaxolone (the…

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Cannabidiol (Epidiolex) for Seizures in LGS

What is Cannabidiol? LGS is tough. Finding information shouldn’t be. That is why we provide information about this and other medications often used in LGS. We hope you find this information useful as you navigate your LGS journey. Cannabidiol (the…

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Lamotrigine for Seizures in LGS

What is Lamotrigine? LGS is tough. Finding information shouldn’t be. That is why we provide information about this and other medications often used in LGS. We hope you find this information useful as you navigate your LGS journey. Lamotrigine (the…

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PACIFIC Research Study

NOT RECRUITING

The PACIFIC Study is a clinical trial for a drug called LP352. This study will assess the safety and tolerability of this drug as well as examine changes in seizure frequency over the 90-day treatment period. The study plans to…

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The Skyway Study for Soticlestat

A Clinical Trial Open to Those With Seizures Associated with LGS

The Skyway Study is a Phase 3 clinical research study of an investigational medication for children, teens, and adults diagnosed with Lennox-Gastaut Syndrome (LGS) who are currently using 0-3 anti-seizure medications to manage symptoms and are still experiencing seizures. The…

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Diazepam Nasal Spray (Valtoco)

New Treatment for Seizure Clusters

What is Diazepam Nasal (Valtoco) Spray? LGS is tough. Finding information shouldn’t be. That is why we provide information about this and other treatments for LGS. We hope you find this information useful as you navigate your LGS journey. Diazepam…

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Midazolam Nasal Spray (Nayzilam)

New Treatment for Seizure Clusters

What Is Midazolam Nasal Spray? LGS is tough. Finding information shouldn’t be. That is why we provide information about this and other medications often used in LGS. We hope you find this information useful as you navigate your LGS journey….

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STARS Research Study

A Clinical Trial Open to Those With Seizures

The STARS (Stand Together Against pRolonged Seizures) Research Study is a clinical trial for a drug called Alprazolam, which is sometimes used to treat seizures. Alprazolam is the active ingredient in Xanax, a commonly known drug. This study is a…

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Felbamate (Felbatol) for Seizures in LGS

What is Felbamate? LGS is tough. Finding information shouldn’t be. That is why we provide information about this and other medications often used in LGS. We hope you find this information useful as you navigate your LGS journey. Felbamate (the…

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List of Treatments for Seizures

This page offers a list of FDA-approved treatments often used in those with LGS. Not all medications used in LGS are listed here. This list reflects U.S. FDA-approved medications. Medications & Behavior in LGS Medication Treatments for Seizures in LGS…

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