Treatments for LGS

PACIFIC Research Study

A Clinical Trial Open to Those with Seizures

The PACIFIC Study is a clinical trial for a drug called LP352. This study will assess the safety and tolerability of this drug as well as examine changes in seizure frequency over the 90-day treatment period. The study plans to…

More

Carisbamate for Seizures

What is Carisbamate? Carisbamate (the generic name), also known as Comfyde (the brand name), is a medication used to treat seizures. When taken orally, Carisbamate can inhibit voltage-gated sodium channels, which may be useful for drug-resistant epilepsy. LGS is tough….

More

The Skyway Study for Soticlestat

A Clinical Trial Open to Those With Seizures Associated with LGS

The Skyway Study is a Phase 3 clinical research study of an investigational medication for children, teens, and adults diagnosed with Lennox-Gastaut Syndrome (LGS) who are currently using 0-3 anti-seizure medications to manage symptoms and are still experiencing seizures. The…

More

STARS Research Study

A Clinical Trial Open to Those With Seizures

The STARS (Stand Together Against pRolonged Seizures) Research Study is a clinical trial for a drug called Alprazolam, which is sometimes used to treat seizures. Alprazolam is the active ingredient in Xanax, a commonly known drug. This study is a…

More

Ganaxolone for Seizures in CDKL5 Deficiency Disorder

New Treatment for CDKL5 Deficiency Disorder (a genetic cause of seizures that can lead to LGS)

What is Ganaxolone? Ganaxolone (the generic name), also known as Ztalmy (the brand name), is a prescription medication used to treat seizures associated with cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder (CDD), a known cause of seizures that can evolve into…

More

Midazolam Nasal Spray (Nayzilam) for Seizure Clusters

What Is Midazolam Nasal Spray? Midazolam (generic name), also known as Nayzilam (the name brand), is a prescription medicine used for the short-term treatment of seizure clusters (also known as acute repetitive seizures). It is a rescue medication in the…

More

Cannabidiol (Epidiolex) for Seizures in LGS

What is Cannabidiol? Cannabidiol (the generic name), also known as Epidiolex (the brand name), is a prescription medicine that is used to treat seizures associated with Lennox-Gastaut syndrome, Dravet syndrome, or tuberous sclerosis complex in patients 1 year of age…

More

Felbamate (Felbatol) for Seizures in LGS

What is Felbamate? Felbamate (the generic name), also known as Felbatol (the brand name), is an anti-epileptic drug that was approved by the Food and Drug Administration (FDA) for the management of focal seizures (previously called partial seizures) and seizures…

More

Lamotrigine for Seizures in LGS

What is Lamotrigine? Lamotrigine (the generic name), also known as Lamictal (the brand name), is a medication used to treat epilepsy and stabilize mood in bipolar disorder. For epilepsy, this includes focal seizures, tonic-clonic seizures, and seizures in Lennox-Gastaut syndrome….

More

List of Treatments for Seizures

This page offers a list of FDA- approved treatments often used in those with LGS. Not all medications used in LGS are listed here. This list reflects U.S. FDA-approved medications. For info on epilepsy treatments in the U.K. visit this…

More