Midazolam Nasal Spray (Nayzilam)

New Treatment for Seizure Clusters

What Is Midazolam Nasal Spray?

LGS is tough. Finding information shouldn’t be. That is why we provide information about this and other medications often used in LGS. We hope you find this information useful as you navigate your LGS journey.

Midazolam (generic name), also known as Nayzilam (the name brand), is a prescription medicine used for the short-term treatment of seizure clusters (also known as acute repetitive seizures). It is a rescue medication in the form of a nasal spray.

Additional Information:

HOW TO GIVE NAYZILAM

NAYZILAM is a ready-to-use nasal spray that can be given by anyone, whenever seizure clusters occur.

The complete steps on how to use NAYZILAM can be found at www.nayzilam.com/how-to-use-nayzilam

Learn more at www.nayzilam.com

NAYZILAM Patient Assistance Program

The NAYZILAM Patient Assistance Program may provide medication at no cost to eligible patients who are unable to pay for their NAYZILAM prescription.

Learn more at www.nayzilam.com/savings

The information here is not intended to provide diagnosis, treatment, or medical advice and should not be considered a substitute for advice from a healthcare professional. The content provided is for informational purposes only. LGS Foundation is not responsible for actions taken based on the information included on this webpage. Please consult with a physician or other healthcare professional regarding any medical or health-related diagnosis or treatment options.

Updated 02/09/26 (KK)