Powering Breakthroughs for LGS
Our multi-year plan to find better treatments and cures for LGS
For the first time, the pieces are in place. The science is ready, the data is growing, and our community is strong. Powering Breakthroughs is our multi-year research plan, and it is built around the questions families actually ask. Everything we do points us towards the LGS 3 Grand Challenges.
Families come first, and researchers follow the family’s lead. That is how we make sure the science answers what matters most to the people living with LGS.
Real Life Impact
The LGS Foundation unites families and researchers to drive faster progress. We measure success in family outcomes, not just papers.
Meet Charlie
“For 42 years we assumed our son was singular in his complex array of medical issues. It was only six months ago that we learned he belongs to a sliver of individuals with LGS. A simple notation made in Charlie’s chart by his neurologist was casually shared by a new primary care physician. A notation that had never before reached us.“ – Luise, Charlie’s Mom
Meet Mason
“We threw ourselves with every ounce of energy we could find into therapies and medical treatments. Countless medications were tried – many that had side effects that made us feel like we were putting out his beautiful light. So many failed to help at all. Some helped for a while then stopped.” – Tricia, Mason’s Mom
Meet Jackson
“We cannot let Jackson out of our sight—ever. We have to intervene or assist him constantly, so there is no freedom. During his waking hours, everything else is pushed to the side. Oftentimes only the critical things get done. Guilt and sadness are frequent parts of our reality.“ – Jeannie, Jackson’s Mom
GIVE today to power breakthroughs
Your gift—no matter the size or method—makes an incredible difference. Thank you for being part of the journey to find cures and improve lives. We recommend consulting with your tax professional or attorney for specific questions regarding tax benefits and how these giving options apply to your situation.
For more information, please contact us at Giving@LGSFoundation.org.
The LGS Foundation is proud to be a top-rated charity, regularly reviewed and held accountable by independent third-party organizations.
The LGS Foundation is a 501(c)3 tax-exempt organization. Your donation is tax-deductible to the fullest extent allowed by law. EIN: 26-2051377
Updated 07/06/26 (AM)