Ganaxolone (Ztalmy)

New Treatment for Seizures in CDKL5 Deficiency Disorder (a genetic cause of seizures that can lead to LGS)

What is Ganaxolone?

LGS is tough. Finding information shouldn’t be. That is why we provide information about this and other medications often used in LGS. We hope you find this information useful as you navigate your LGS journey.

Ganaxolone (the generic name), also known as Ztalmy (the brand name), is a prescription medication used to treat seizures associated with cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder (CDD), a known cause of seizures that can evolve into LGS.

Watch Now: Overview of Ganaxolone for LGS

Presented by: Michael Chez, MD, Pediatric Epileptologist, Sutter Health, California

*Dr. Michael Chez is a Pediatric Epilepsy Expert and regularly treats LGS patients. This video was recorded in early 2022 at the request of the LGS Foundation to provide information to our family members about this medication. The Foundation does not endorse this or any product and is here only to provide information relevant to patient families. 

The information here is not intended to provide diagnosis, treatment, or medical advice and should not be considered a substitute for advice from a healthcare professional. The content provided is for informational purposes only. LGS Foundation is not responsible for actions taken based on the information included on this webpage. Please consult with a physician or other healthcare professional regarding any medical or health-related diagnosis or treatment options.


Updated: 2/20/23