Optimizing Stimulation Parameters for LGS Neuromodulation (OPTISTIM+) Dr. Linda Dalic, PhD University of Melbourne, Australia Neurologist/Epileptologist Highlights: Seeks a better understanding of epilepsy neuromodulation in LGS patients. Explores the role of different target and stimulation parameters for LGS patients….
Preclinical Optimization of a Non-Invasive Approach to DBS in LGS Highlights: Assesses low-intensity ultrasound for seizure treatment. Targets the centromedian thalamus in mice that have seizures from LGS. Determines the feasibility of applying focused ultrasound as a non-invasive substitute for…
Neurostimulation to Remodel Sleep Architecture in LGS Dr. Aaron Warren, PhD Brigham and Women’s Hospital, Harvard Medical School Highlights: Enrolled 20 patients participating in an ongoing clinical trial of dual thalamic and cortical responsive neurostimulation (RNS) Determining the correlation between…
Sleep Evaluation for Children with LGS – A Pilot Study Dr. Gita Gupta, MD University of Michigan Highlights: Assesses sleep in children with LGS using a combination of in-clinic and home evaluations, wearable devices, and questionnaires to reveal medical and…
The LGS Foundation is harnessing the power of the patient family community to ensure that research, care, support services, education, and awareness of LGS are relevant for those living with LGS and their loved ones. Learn About LGS from those…
The LGS Foundation was proud to host the DELVE Meeting on Developmental and Epileptic Encephalopathies (DEEs) & Lennox-Gastaut Syndrome (LGS) An Externally-Led Patient-focused drug development (PFDD) meeting on DEEs & LGS On November 1, 2019, the LGS Foundation convened the…
Apply for an lGS Research Grant 365 days a year The LGS Foundation accepts unsolicited proposals year-round to seed new basic, translational, and clinical research projects on LGS. Projects may be funded at the $25,000, $50,000, or $75,000 level. Projects…
The following are key publications in LGS that are open access and free of charge. 2022: Seizure Clusters: Practical Aspects and Clinical Strategies to Care for Patients in the Community. (Penovich PE, Glauser T. Seizure clusters: Practical aspects and clinical…
What is a Clinical Trial? Clinical trials and research studies are done to scientifically evaluate a medical or surgical intervention. They are the primary way that researchers find out if a new treatment, like a new drug, diet, surgery, or…
The LGS Foundation is dedicated to funding the highest caliber research on LGS We focus on research projects to find new treatments and improve the quality of life for individuals impacted by Lennox-Gastaut Syndrome. The LGS Foundation places a high…
