The LGS DISCOVER Study

A Clinical Study for Children and Adults with Lennox-Gastaut Syndrome

The LGS DISCOVER study, also identified as the YKP509C003 study, is a clinical trial for pediatrics and adults with Lennox-Gastaut Syndrome (LGS).

The LGS DISCOVER study will evaluate whether an investigational medicine called carisbamate, when given along with other anti-seizure medications for epilepsy, can decrease the number of seizures in LGS patients 4-55 years of age who are on one or more anti-seizure medications.

Study Sites in the United States:

  • Johns Hopkins Hospital, Baltimore, MD
  • Duke University Clinical Research, Durham, NC
  • Stanford University, Palo Alto, CA
  • Children’s Hospital of Philadelphia, Philadelphia, PA
  • Midatlantic Epilepsy and Sleep Center, Bethesda, MD
  • Northeast Regional Epilepsy Group, Hackensack, NJ
  • Pediatric Epilepsy and Neurology Specialists, Tampa, FL

For more information about the LGS DISCOVER study, please contact sklsicarisbamate@sklsi.com.


Additional Information:

View the LGS DISCOVER Study Brochure 

Visit the LGS DISCOVER Study Website


The information here is not intended to provide diagnosis, treatment, or medical advice and should not be considered a substitute for advice from a healthcare professional. The content provided is for informational purposes only. LGS Foundation is not responsible for actions taken based on the information included on this webpage. Please consult with a physician or other healthcare professional regarding any medical or health-related diagnosis or treatment options.


Updated 06/05/26 (AM)