About LGS
- Like many rare conditions, Lennox-Gastaut Syndrome can be a complete mystery when you first hear about it. Explore this section to get a thorough understanding of LGS—including its causes, symptoms, diagnosis and treatment.
New to LGS
- A diagnosis of LGS is deeply unsettling and can leave you at a loss as to where to turn for help and guidance. We’re here for you. In this section you will find information, resources, and communities of support for the challenging road ahead.
For Families
- If a loved one is living with LGS, the entire family shares in the difficult journey. How can you keep them safe? Find appropriate medical care? Get the support you need? This section gives answers to these and other critical questions.
About Research
- Even as our understanding of LGS grows, there is so much more to learn. From research grants to conferences, from publications to voice of the patient family, this section provides avenues for furthering your knowledge and impact.
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- Host a fundraiser. Volunteer at an event. Shop our LGS store. These are just some of the ways you can lend your personal support to our mission. Check out this section to get started.
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Home / Team / Heather Mefford, MD, PhD

Heather Mefford, MD, PhD

St. Jude Children's Hospital

Heather Mefford is a Full Member of the Center for Pediatric Neurological Disease Research at St. Jude Children’s Research Hospital. She runs a research laboratory dedicated to gene discovery in pediatric disease, with a major focus on pediatric epilepsies. Her work uses cutting-edge genomic technologies and has helped define the genetic landscape of epileptic encephalopathies with studies reporting novel copy number variants and numerous novel disease-causing genes. She identified and characterized several novel deletion and duplication syndromes due to recurrent CNVs. She was a co-PI for several of the Epi4K consortium projects and co-chairs the ClinGen Neurodevelopmental Disorder Clinical Domain Working Group and Epilepsy Gene Curation Working Group. She serves on the Professional Advisory Board for LGSF.